Any observed effects from the vaccine?

[retropean]

32-year-old male here. Got the Johnson and Johnson shot. Extreme shakes and flu like symptoms 12 hours after the shot that lasted through the night, but after that it’s been smooth sailing.

[ripvanrando]

Originally Posted by mistermo

I can't know your career experience, nor can you know mine. Name another vax or drug that's been FDA tested on tens of millions in PhIII or earlier trials? I know of none.



#1-The CDC is not the FDA. Please, let's not intertwine testing/efficacy/safety (FDA) with messaging/rollout/distribution (CDC).



#2-The elderly and most at risk were most definitely given earlier access than others.



#3-Certainly, one objective of the vaccine is to prevent death. By no stretch of the imagination is that the primary objective. There's MANY ill effects, well documented, short of death. Yet, many remain unknown. Many viruses reappear later in life with other, more significant effects. HPV->cancer, Hepatitis->liver failure, Chicken Pox->shingles, HIV->AIDS, and more.

While there's little probability that the young (or any of us) may die (today), avoidance of death is not the primary rationale for most vaccines. There's a litany of other ill effects that vaccine will guard against, including transmission to others. It's well understood that young are vectors of transmission. Until they are vaccinated, it will continue to transmit and mutate.

Anything we can do (safely and effectively) to avoid transmission to ourselves and others, is a no-brainer.



Fully agree as long as people understand the difference between anecdotal example and statistically proven data. It's my view that many do not.

I know of several locally who refuse vaccine after a local woman died of a stroke two weeks after her vaccine. In their minds, there's a correlation despite lack of proof. Emotional response vs informed response.

First, you either misunderstood or mischaracterized my statement about the priority of vaccine administration. I stand by my opinion that the first to have received the vaccine should have been the elderly exclusively, especially those with conditions. I never said or imply others should not take it. Note, I am vaccinated.

With respect to tens of millions of Subjects in Phase 3 clinicals for Moderna, PFE, or JNJ. Do you want to check your numbers? You are making a really, really silly statement. It was tens of thousands, not millions.

You quibbled about my statement WRT CDC. Let me quibble with you. FDA did not APPROVE any of these vaccines. There was no NDA. They were authorized for emergency use. There is a big difference. You said there was never a drug or vaccine tested so completely as these vaccines. There is quantity and there is time. From subject enrollment to Emergency Authorization, we had several months. Normally, we have years. On that basis alone, your statement incorrect. Your tens of millions is off by at least 2 orders of magnitude. I recall some biological products with similar enrollment levels but over a much longer duration of time. I have had access to this data for at least 4 of the largest drug companies. You are correct that most trials do not have as many subjects in PhaseIII

If someone wishes to purview the reported adverse events, this is where vaccine events are reported.

https://vaers.hhs.gov/data.html

[Bentley]

I just became "completely vaccinated", that said who really knows, but I am glad that I am participating.

I had the Pfizer vaccine, I did not have any real effects, other than a sore arm at the injection site, but I do have some advice.

My daughter's doc gave her some advice, which I also followed, basically it is to hydrate (over hydrate) the day before and the day of the shot. I cannot claim that this is scientifically verified, but I had no "side effects" from the injection.....

[ripvanrando]

It is speculated the Pfizer vaccine has few side effects because the dose is much less than the Moderna.

I went for the Pfizer. I know them and the plants very well.

[Coffee Rider]

I got Pfizer and my arm was sore around the injection site for a day or so after each shot, but that was really it. Based on everyone I personally know, it's a total crapshoot as to whether you have side effects from the vaccine. I suppose it's analogous the virus in that regard, with symptoms ranging between none and death. Although this is not medical grade, I've had some water retention after the second shot, but I can't really complain about it.

[wc1934]

Pfizer
Shoulder was a bit sore after the first shot (maybe as a result of where the needle was inserted?)
Second shot - no problems
Rode after each shot.

[MagicHour]

I'm 52 - got J&J single dose. The following evening 24hrs hours after I felt achy and tired like I had a flu coming on but woke up fine next morning, that was it not bad at all. Feels like some normalcy is coming to NYC and did my first city ride yesterday without a mask, although, if I'm walking around in a crowded area I'm still wearing one.

[2000m2]

I'm 40 and got the Pfizer vaccine. Not too bad overall. Thank you Veterans Administration.
First one - just a sore shoulder and a little fatigue.
Second one - didn't sleep very well, dull headache most of the next day along with body aches and fatigue for a couple more days.

[yinzerniner]

Hilltopperny, sorry but you're completely misinformed in this arena

Originally Posted by Hilltopperny

Moderna closes its short term trials in 2022 and Pfizer closes its short term trials in 2023.

This is incorrect. The Trials already concluded - the 2022 and 2023 dates were supplied by the different manufacturers for "estimated end date" in official documentation when submitting the information for inspection.

Conflating the estimated trial end date with the already completed trials is like saying you've already made $3,000,000 when you apply for a 30yr mortgage and estimate your income at $100,000 a year.
See reference links below:
https://www.reuters.com/article/fact...-idUSL1N2M70MW
https://clinicaltrials.gov/ct2/show/NCT04368728
https://clinicaltrials.gov/ct2/show/NCT04470427

Originally Posted by Hilltopperny

This is a new technology developed by DARPA and does not make any specific claims other than it may cause you to be less symptomatic.

The tech was started by DARPA over a decade ago, and the specific claims aren't about the tech since there are NO specific claims. The DARPA tech was used in conjunction with Pfizer and Moderna to speed up the possibility of antibody reactions and production, which then had to be tested as effective in limiting the symptoms that caused illness and death in covid patients.
https://webcache.googleusercontent.c...&ct=clnk&gl=us

Originally Posted by Hilltopperny

To act as if people are crazy or misinformed is a bit of a stretch. I would argue those blindly participating in the largest human trials in world history without any animal studies prior is more crazy given there are known tested drugs that are cheap and readily available like Budesonide and Ivermectin. Both of which are cheap and effective FDA approved medications.

Again, they aren't trials since the trials have already commenced. And the drugs you listed do exist, but they only treat the symptoms after you contract COVID. The goal of the vaccine is totally different - it's to stop the spread, which is highly likely due to the nature of the disease and the possibility of asymptomatic contagiousness. And ivermectin efficacy is spotty at best....
https://www.economist.com/science-an...vid-19-at-home
https://www.fda.gov/consumers/consum...event-covid-19

Originally Posted by Hilltopperny

94% of listed Covid deaths had an average of 2.4 co morbidities which is often overlooked. That is a very significant data point given that those people had a multitude of deadly health issues.

You gonna die on this hill again? This has already been debunked over and over and over.
https://www.medpagetoday.com/infecti.../covid19/85741

Originally Posted by Hilltopperny

50 and under have an over 99% survival rate before the use of the two drugs I listed and if you are older without co morbidities you have an over 99% survival rate as well. I realize this isn’t popular opinion, but this is the data.

The reason that it's not a popular opinion is because it's faulty logic and delegitimizes unnecessary early deaths. Yes, 50 and under have a 99% survival rate, but that doesn't take into account the resources required for survival, nor the long term health ramifications, nor the deaths that DO occur. As of right now roughly 1 in 10 Americans under 50 have caught covid, so ~20 million. Of that 1% died from covid, so 200,000 deaths and many more with long term health issues. Or, you can do just the bare minimum based on ACTUAL science and research to limit as many of those early deaths as possible.

Originally Posted by Hilltopperny

95% of people who get it have lasting antibodies according to the NIH data as well.
https://www.nih.gov/news-events/nih-...overy-covid-19

Antibodies don't last forever, and the virus is always mutating, but it needs hosts to continue.

The more people ignore or downplay the science the more they'll hurt others. If you're fine with casual cruelty to strangers then have at it.

[XXtwindad]

Fortuitous thread.

I got my second Pfizer dose yesterday. Achy and a little bit of a headache.

But the timing is pretty bad. My Partner left for a much needed vacation for a week early this morning. So I’m looking after my six-year old twin girls by myself. It kind of feels like the curtain is coming up on a Hall & Oates show and the skinny blond dude has taken a hiatus.

But, this morning, as one daughter snuggled in my lap, tearily asking to call her “Ima,” the other daughter marched downstairs with nary a glance. When I asked her where she was going, she said “to make breakfast for me and my sister.”

When I followed up that question and asked for a hug, she said “No thanks. I’m busy.”

So the good news is that the backup singer appears to be pretty competent 😉

[reuben]

Originally Posted by mistermo

Fully agree as long as people understand the difference between anecdotal example and statistically proven data.

From my math perspective, the statistics are an accumulation (distribution) of anecdotal data. For example - Where did you hurt, how bad was it, how long did it last, did you go to the hospital or call your doctor? Other than quantifiable things like blood cell counts and body temperature (which varies among individuals), it's all anecdotal. But - given a large enough sample, a picture/distribution emerges.

I'm not arguing with you, just adding my non-virologist but science based perspective.

Two anecdotes mean nothing. Two thousand - now we're starting to get a picture, i.e. "statistically proven data". Two hundred thousand - now we're talkin'.

[reuben]

About 24 hours after my second shot I considered buying a carbon frame with disc brakes and electronic shifting.

I'm all better now.

[Hilltopperny]

Originally Posted by yinzerniner

Hilltopperny, sorry but you're completely misinformed in this arena


This is incorrect. The Trials already concluded - the 2022 and 2023 dates were supplied by the different manufacturers for "estimated end date" in official documentation when submitting the information for inspection.

Conflating the estimated trial end date with the already completed trials is like saying you've already made $3,000,000 when you apply for a 30yr mortgage and estimate your income at $100,000 a year.
See reference links below:
https://www.reuters.com/article/fact...-idUSL1N2M70MW
https://clinicaltrials.gov/ct2/show/NCT04368728
https://clinicaltrials.gov/ct2/show/NCT04470427


The tech was started by DARPA over a decade ago, and the specific claims aren't about the tech since there are NO specific claims. The DARPA tech was used in conjunction with Pfizer and Moderna to speed up the possibility of antibody reactions and production, which then had to be tested as effective in limiting the symptoms that caused illness and death in covid patients.
https://webcache.googleusercontent.c...&ct=clnk&gl=us


Again, they aren't trials since the trials have already commenced. And the drugs you listed do exist, but they only treat the symptoms after you contract COVID. The goal of the vaccine is totally different - it's to stop the spread, which is highly likely due to the nature of the disease and the possibility of asymptomatic contagiousness. And ivermectin efficacy is spotty at best....
https://www.economist.com/science-an...vid-19-at-home
https://www.fda.gov/consumers/consum...event-covid-19


You gonna die on this hill again? This has already been debunked over and over and over.
https://www.medpagetoday.com/infecti.../covid19/85741


The reason that it's not a popular opinion is because it's faulty logic and delegitimizes unnecessary early deaths. Yes, 50 and under have a 99% survival rate, but that doesn't take into account the resources required for survival, nor the long term health ramifications, nor the deaths that DO occur. As of right now roughly 1 in 10 Americans under 50 have caught covid, so ~20 million. Of that 1% died from covid, so 200,000 deaths and many more with long term health issues. Or, you can do just the bare minimum based on ACTUAL science and research to limit as many of those early deaths as possible.


Antibodies don't last forever, and the virus is always mutating, but it needs hosts to continue.

The more people ignore or downplay the science the more they'll hurt others. If you're fine with casual cruelty to strangers then have at it.

So, I am to believe that a new technology that is rushed has gone through extensive long term testing? It hasn’t even been around long enough in the short term to be honest. You guys are funny in trying to explain this away. A normal vaccine takes an average of 7 years to come to market. This took 7 months and ignored cheap available drugs like Budesonide and Ivermectin. If the public was aware of them this would not have had emergency use authorization as it wouldn’t have been needed.

https://www.thelancet.com/journals/l...160-0/fulltext

https://www.ox.ac.uk/news/2021-02-09...patients-study

https://www.sciencedirect.com/scienc...66354220302011

Sent from my iPhone using Tapatalk

[reuben]

Originally Posted by XXtwindad

But the timing is pretty bad. My Partner left for a much needed vacation for a week early this morning. So I’m looking after my six-year old twin girls by myself. It kind of feels like the curtain is coming up on a Hall & Oates show and the skinny blond dude has taken a hiatus.

But, this morning, as one daughter snuggled in my lap, tearily asking to call her “Ima,” the other daughter marched downstairs with nary a glance. When I asked her where she was going, she said “to make breakfast for me and my sister.”

When I followed up that question and asked for a hug, she said “No thanks. I’m busy.”

So the good news is that the backup singer appears to be pretty competent 😉

Awesome sauce!

[Dead Man]

pfizer... a mildly sore shoulder for a couple days twice, tis all