I was experiencing some prostate issues after riding Fizik aliantes for years so I took a chance and tried one of the new Shimano Pro saddles. I'm riding the 142mm Turnix AF which features a large cutout and it's been amazing. No more issues and it's actually comfortable. Best of all, Shimano offers a 30 day return guarantee so I was able to try the 132mm version for 2 weeks and swap it for the wider one. Shimano has 3 or 4 different types of saddles to choose from. They run about $120 for the titanium rails and $200 for carbon.
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