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I think that you get it, leaving just a bit of freeplay so that flexing frame tubes don't cause the cable to pull the derailer repeatedly against the hard stop of the limit screw, which would fatigue cable strands rapidly.
I usually back off the limit screw at most a quarter of a turn from the last-gear position, and always after the cable adjustment is finalized.
One more thing is when riders swap wheels and then make a small cable adjustment to correct the indexing adjustment, but ignore that the limit screw now is not free of the derailer's movement to the last cog, or is now too far out to limit the derailer's movement past the last index position.
I mention this issue because I often work on bikes that only shops have worked on, and find limit screws set too far in, as if the trauma to the cable and it's adjustment might be expected to bring in more service work. Probably though it is just the hasty or precautionary setting of the screw, seasonal workloads being what they are(?).
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