I have a Moots and it is without a doubt the best bike I've ever had. I do ride my Cannondale more these days though. I got the Moots to be an aggressive racing bike while the Synapse is more of an upright ride. The Moots was a perfect balance of comfort and speed. Nothing beats a good steel bike for comfort though. So I'd say you got nothing to worry about thought if you get a chance to try one do it.
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