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I've been using adapters to run a non-Boost wheelset in a Boost frame and fork for 4 years now. It works fine but the chainline will be off since the cassette is 3 mm inboard of recommended. I haven't had any issues but it will wear out your drivetrain faster. It's also kind of a pain getting the spacers lined up on the axle when you put the wheel back on after a tire change. I cracked one of my rims so I'm using it as an excuse to finally get a Boost wheelset. If it weren't for that I'd still run the adapters.
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