this is known to happen on titanium frames and those with chromed dropouts. the dropout is very hard and the QR doesn't "bite" hard enough to prevent slippage.
ditch those hope skewers, yes, they are very good, but in this situation you require some extra clamping force, get a set of dura ace or record closed cam skewers and clamp em down.
it may also help to scuff up the dropout faces, both inner and outer to give the hub face and QR a better chance of getting some friction.
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